USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: MTND_HUMAN USC-OGP 2-DE database:  MTND_HUMAN MTND_HUMAN General information about the entry View entry in simple text format Entry name MTND_HUMAN Primary accession number Q9BV57 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Submergence-induced protein-like factor; Short=Sip-L;. Gene name Name=ADI1 {ECO:0000255|HAMAP-Rule:MF_03154} Synonyms=MTCBP1 {ECO:0000255|HAMAP-Rule:MF_03154} ORFNames=HMFT1638 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1318: pI=5.55; Mw=19701 Cross-references UniProtKB/Swiss-Prot Q9BV57; MTND_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MTND_HUMAN Primary accession number Q9BV57 Secondary accession number(s) D6W4Y3 Q53HW3 Q53QD3 Q57YV7 Q68CK2 Q6ZSF7 Q7Z512 Q96P85 Q9NV57 Sequence was last modified on  June 1, 2001 (version 1) Annotations were last modified on  March 15, 2017 (version 147) Name and origin of the protein Description RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Submergence-induced protein-like factor; Short=Sip-L; Gene name Name=ADI1 {ECO:0000255|HAMAP-Rule:MF_03154} Synonyms=MTCBP1 {ECO:0000255|HAMAP-Rule:MF_03154} ORFNames=HMFT1638 Encoded on Name=ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}; Synonyms=MTCBP1 {ECO:0000255|HAMAP-Rule:MF_03154}; ORFNames=HMFT1638 Keywords 3D-structure; Alternative splicing; Amino-acid biosynthesis; Cell membrane; Complete proteome; Cytoplasm; Dioxygenase; Direct protein sequencing; Iron; Membrane; Metal-binding; Methionine biosynthesis; Nucleus; Oxidoreductase; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AB158319; BAD10866.1; -; mRNA EMBL AF087863; AAP97173.1; -; mRNA EMBL AB073609; BAD38646.1; ALT_INIT; mRNA EMBL AK001775; BAA91901.1; -; mRNA EMBL AK127473; BAC86996.1; -; mRNA EMBL AK222467; BAD96187.1; ALT_INIT; mRNA EMBL AC142528; AAX82038.1; -; Genomic_DNA EMBL AC114810; AAY24022.1; -; Genomic_DNA EMBL CH471053; EAX01064.1; -; Genomic_DNA EMBL CH471053; EAX01065.1; -; Genomic_DNA EMBL BC001467; AAH01467.1; -; mRNA EMBL AF403478; AAL25800.1; ALT_INIT; mRNA CCDS CCDS1653.1; -. [Q9BV57-1]; . CCDS CCDS77380.1; -. [Q9BV57-2]; . RefSeq NP_001293006.1; NM_001306077.1. [Q9BV57-2]; . RefSeq NP_060739.2; NM_018269.3. [Q9BV57-1]; . UniGene Hs.502773; -; . PDB 4QGN; X-ray; 3.05 A; A=1-179 PDBsum 4QGN; -; . ProteinModelPortal Q9BV57; -; . SMR Q9BV57; -; . BioGrid 120547; 17; . IntAct Q9BV57; 3; . STRING 9606.ENSP00000333666; -; . DrugBank DB02325; Isopropyl Alcohol; . iPTMnet Q9BV57; -; . PhosphoSitePlus Q9BV57; -; . BioMuta ADI1; -; . DMDM 74733289; -; . EPD Q9BV57; -; . MaxQB Q9BV57; -; . PaxDb Q9BV57; -; . PeptideAtlas Q9BV57; -; . PRIDE Q9BV57; -; . TopDownProteomics Q9BV57-1; -. [Q9BV57-1]; . TopDownProteomics Q9BV57-2; -. [Q9BV57-2]; . DNASU 55256; -; . Ensembl ENST00000327435; ENSP00000333666; ENSG00000182551. [Q9BV57-1]; . Ensembl ENST00000382093; ENSP00000371525; ENSG00000182551. [Q9BV57-2]; . GeneID 55256; -; . KEGG hsa:55256; -; . UCSC uc002qxp.5; human. [Q9BV57-1]; . CTD 55256; -; . DisGeNET 55256; -; . GeneCards ADI1; -; . HGNC HGNC:30576; ADI1; . HPA HPA035403; -; . HPA HPA035404; -; . MIM 613400; gene; . neXtProt NX_Q9BV57; -; . OpenTargets ENSG00000182551; -; . PharmGKB PA143485291; -; . eggNOG KOG2107; Eukaryota; . eggNOG COG1791; LUCA; . GeneTree ENSGT00390000008195; -; . HOVERGEN HBG081992; -; . InParanoid Q9BV57; -; . KO K08967; -; . OMA QWIRIEV; -; . OrthoDB EOG091G0OM4; -; . PhylomeDB Q9BV57; -; . TreeFam TF300231; -; . Reactome R-HSA-1237112; Methionine salvage pathway; . UniPathway UPA00904; UER00878; . ChiTaRS ADI1; human; . GeneWiki ADI1; -; . GenomeRNAi 55256; -; . PRO PR:Q9BV57; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000182551; -; . CleanEx HS_ADI1; -; . ExpressionAtlas Q9BV57; baseline and differential; . Genevisible Q9BV57; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0010309; F:acireductone dioxygenase [iron(II)-requiring] activity; TAS:Reactome; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0016491; F:oxidoreductase activity; IDA:UniProtKB; . GO GO:0019509; P:L-methionine salvage from methylthioadenosine; IDA:UniProtKB; . Gene3D 2.60.120.10; -; 1; . HAMAP MF_03154; Salvage_MtnD_euk; 1; . InterPro IPR004313; ARD; . InterPro IPR027496; ARD_euk; . InterPro IPR014710; RmlC-like_jellyroll; . InterPro IPR011051; RmlC_Cupin; . PANTHER PTHR23418; PTHR23418; 1; . Pfam PF03079; ARD; 1; . SUPFAM SSF51182; SSF51182; 1; .

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